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Product Category

Reagent Grade

DEXTRAN SULFATE 8000 Na

Product Code: DXSE-5201

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Intended For Use In Commercial Manufacturing, Diagnostic And Laboratory Applications


Dextran Sulfate 8000 Na is a polyanionic derivative of dextran, produced by the esterification of the glucose polymer (glucan polysaccharide) with chlorosulphonic acid. Dextran fractions are characterized by their average MW and MW distribution with predominantly 1-6 glycosidic bones and 5% or less of 1-3 branching. Each base dextran polymer has characteristics unique to the specific strain of bacteria from which is was derived. In addition to variables in molecular weight and branching, the level of sulfonation adds to the unique character and performance of the finished product in terms of its intended end use. Dextran Sulfate 8000 Na, 8000 MW is used in the solubilization and purification process of protein molecules intended for use in a final drug product. Dextran is neutral in pH and soluble in water. It is easily filtered and biodegradable.

Product Specifications

ANALYSIS

SPECIFICATIONS
Appearance (Color)  
Off White to Light Yellow
Appearance (Form)  
Powder
Chloride Content ≤ 1000 ppm
DNase-Endo/Exonuclease Pass
DNase - Nickase Pass
Free Inorganic Sulfate ≤ 0.2%
Glucose 35-48%
Identity (colormetric) Pass
Insoluble Iron ≤ 2.0%
Loss on Drying ≤ 10.0%
Microbial Contamination ≤ 10 CFU/g
pH 1% aqueous 5.0 – 7.5
Protease Detection Pass
Residue on Egnition 35 – 50%
Residue Pyridine ≤ 2.0%
Specific Rotation 20°C 75-105°
Total Sulfur Content 17.0-20.0%
UV Absorabance 360nm 20% aqueous ≤ 0.9 Abs UN
Viscosity 1.0M NaCl / 25°C 0.018-0.032 

Printable Version

List of C of As files
DXSE-0124-00000 CoA DXSE-0123-00026.pdf
DXSE-0124-00000 CoA DXSE-0123-00020.pdf
DXSE-0124-00000 CoA DXSE-0123-00019.pdf

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COAs and Tech Docs

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DXSE-5201

CAS #: 9011-18-1

Formula:  (C6H7Na3O14S3)n

pH @ 20°C: 5.0 - 7.5

F.W.: 8000 g/mol

General Product Description:

  • Dextran Sulfate 8000 Na is an off white to light yellow powder 

  • Molecular Formula: (C6H7Na3O14S3)n 

  • Molecular Weight: 8000 g/mol.

  • CAS Number: 9011-18-1

  • There are no known major food allergens (as defined by FDA and WHO) in the manufacture of this product. 

  • BioSpectra certifies that all Dextran Sulfate 8000 Na, DXSE-5201 manufactured at BioSpectra and its raw materials are not derived from or come in contact with animal parts, products, and/or byproducts. 

  • Dextran Sulfate 8000 Na manufactured at BioSpectra and any raw materials used in the manufacture of Dextran Sulfate 8000 Na at BioSpectra are not subject to genetic modification.

  • Synonyms: Dextran, Hydrogen Sulfate, Sodium Salt 



Compliance:

Material represented by this grade is suitable to be used only as the following: Quality System Manufactured Process Chemical for use in further manufacturing or as a reagent chemical for commercial manufacturing, diagnostic and laboratory research. The material represented by this grade is not suitable to be used as an Excipient, Active Pharmaceutical Ingredient, Drug, Drug Product or household item. 

Retest Date:

The recommended shelf life for Dextran Sulfate 8000 Na is three years from the date of manufacture.

Storage and Shipping Conditions:

Store at Room Temperature 10-30° C

Package Sizes:

10kg, 25 kg and 50 kg pails.

 

Additional Packaging Information

https://www.biospectra.us/technical/packaging