Quality Management System Manufactured
ISO Certified
Tris (Tromethamine)
USP, EP, ChP, JPC
Product Code: TRIS-6202
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BioBuffer Solution Brand Product
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Product Code: TRIS-6202
Suitable for use in biological and biotech chemical process applications from R&D through scale cGMP production.
Tromethamine (Tris) is commonly used as a buffer and excipient in downstream biological applications during the manufacture of drug products. Tris is considered a Good's buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.
CAS #: 77-86-1
Formula: NH2C(CH2OH)3
F.W.: 121.14 g/mol
Product Specifications
| Analysis | Specifications | ||
|---|---|---|---|
|
Passes Test | ||
|
99.0 - 100.5% | ||
| Chloride (ChP/EP) | < = 100 ppm | ||
| Clarity and Color of Solution (ChP/JPC) | Passes Test | ||
| Heavy Metals (Pb) (ChP/JPC) | < = 8 ppm | ||
| Identification, IR (USP-A/ChP-3/EP-C) | Conforms to Reference Standard | ||
| Identification A (EP), Alkalinity (ChP), pH (5%) (USP/EP) | 10.0 - 11.5 | ||
| Identification A (JPC) | Passes Test | ||
| Identification B (USP/ChP-1) | Passes Test | ||
| Identification B (EP), Melting Range (USP/ChP/JPC) | 168 - 172°C | ||
| Identification B (JPC) | Passes Test | ||
| Identification C (USP) | Passes Test | ||
| Identification D (EP/ChP-2) | Conforms to Reference Standard | ||
| Loss on Drying (USP/ChP/EP/JPC) | < = 0.5% | ||
| pH (1 in 100) (JPC) | 10.3 - 10.7 | ||
| Related Substances (ChP/EP) | < = 1.0% | ||
| Residue on Ignition/Sulfated Ash (USP/ChP/EP/JPC) | < = 0.1% | ||
|
< = 1.6 ppm < = 10 ppm < = 15 ppm |
Key Product Features:
- Appears as a white crystalline powder
- GMP manufactured in accordance with the QMS
- Manufactured in an enzyme free, hormone free and animal free environment
- Contains no major food allergens (as defined by FDA and WHO)
- The final product and its raw materials are not derived from nor come into contact with animal parts, animal products, and/or animal byproducts or derivatives.
- Is not subject to genetic modification
- Synonyms: Trometamol; THAM; Tris (Hydroxyethyl) Aminomethane; Trisaminol; Trismethylolaminomethane; 2-Amino-2(Hydroxymethyl) propane-1,2-diol; Tromethamine
Shelf-Life Policy:
Please inquire for information regarding shelf life.
Storage & Shipping:
Refer to SDS.
Package Sizes:
1kg, 5kg, 10kg, 25kg, and 50kg
Bulk GMP Fine Chemicals exclusively manufactured in North America
American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.