Tris, USP, EP, ChP, JPC

BioBuffer Solution Brand Product

Process Chemical

ISO Certified Quality Management System

Tris / Tromethamine

Meets USP/EP/ChP/JPC

Product Code: TRIS-6202

Product Inquiry COAs Spec Sheet

Click the button above for pricing, lead times, MOQs and other inquiries.

Product Inquiry

Product(s) of Interest *

First Name *

Last Name *

Title & Position in Company *

Email *

Your Direct Phone Number & Country Code *

Name of Your Company *

Website of Your Company *

Address of Company *

Country where product is to be used *

Name of Your Customer – the End User *

Website of Your Customer – the End User *

Intended Application/Use if known

Package Size Requested *

Estimated Release Quantity per PO in Liters or Kgs *

Estimated Annual Demand in Liters or Kgs *

Regulatory or Compendial Requirements *

INCO Terms requested *

Available Package Sizes – Inquire for Pricing (Minimum Order Quantities May Apply)
100g	500g	1kg	5kg	10kg	25kg	50kg
Inquire	Inquire	Inquire	Inquire	Inquire	Inquire	Inquire

Product Code: TRIS-6202

Suitable for use in biological and biotech chemical process applications from R&D through scale cGMP production.

Tris / Tromethamine is commonly used as a buffer and excipient in downstream biological applications during the manufacture of drug products. Tris is considered a Good's buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

CAS #: 77-86-1
Formula: NH₂C(CH₂OH)₃
F.W.: 121.14 g/mol

Product Specifications

Analysis

Specifications

Appearance of Solution

Passes Test

Assay, Dried Basis

99.0 - 100.5%

Chloride

< = 100 ppm

Clarity and Color of Solution

Passes Test

Heavy Metals (Pb)

< = 8 ppm

Identification, IR (USP-A/EP-C/ChP-3)

Conforms to Reference Standard

Identification A (EP), pH (5%) (USP/EP)

10.0 - 11.5

Identification A (JPC)

Passes Test

Identification B (USP/ChP-1)

Passes Test

Identification B (EP), Melting Range (USP/ChP/JPC)

168 - 172°C

Identification B (JPC)

Passes Test

Identification C (USP)

Passes Test

Identification D (EP/ChP-2)

Conforms to Reference Standard

Loss on Drying

< = 0.5%

pH (1 in 100)

10.3 - 10.7

Related Substances

< = 1.0%

Residue on Ignition / Sulfated Ash

< = 0.1%

Trace Metals

Arsenic (As)

Iron (Fe)

Nickel (Ni)

< = 1.6 ppm

< = 10 ppm

< = 15 ppm

Printable Version

Key Product Features:

Appears as a white crystalline powder
Manufactured in accordance with the ISO Certified Quality Management System
Manufactured in an enzyme free, hormone free and animal free environment
Contains no major food allergens (as defined by FDA and WHO)
The final product and its raw materials are not derived from nor come into contact with animal parts, animal products, and/or animal byproducts or derivatives.
Is not subject to genetic modification
Synonyms: Trometamol; THAM; Tris (Hydroxyethyl) Aminomethane; Trisaminol; Trismethylolaminomethane; 2-Amino-2(Hydroxymethyl) propane-1,2-diol; Tromethamine

Shelf-Life Policy:

Please inquire for information regarding shelf life.

Storage & Shipping:

Refer to SDS.

Package Sizes:

1kg, 5kg, 10kg, 25kg, and 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.