Temporarily unavailable, may be replaced with product code THCL-4251.
Process Chemical

ISO Certified Quality Management System

Tris HCL

BET*, ISO GMP

Product Code: THCL-6251

*Bioburden and Endotoxin Tested

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Product Code: THCL-6251
Suitable for use in biological and biotech chemical process applications from R&D through scale production.

Tris Hydrochloride is a stabilizing buffer in biological applications such as electrochromatography, UV analysis and HPLC. It is used to adjust and stabilize the pH ranges for gels used in electrophoresis applications. Tris Hydrochloride is extensively used as a biological buffer or a component of buffer solutions.

CAS #: 1185-53-1
Formula: NH2C(CH2OH)3·HCl
F.W.: 157.60 g/mol

Product Specifications

 

Analysis Specifications
Absorbance (1M)

260nm

280nm

400nm

< = 0.05 a.u.

< = 0.05 a.u.

< = 0.01 a.u.

Appearance and Color  
White Crystalline Powder
Assay, Dried Basis (NaOH Titration)  
99.5 - 101.0%
Cytotoxicity Passes Test
Endotoxin < = 2.5 EU/g
Enzymes

DNase Exonuclease

DNase Endonuclease

RNase 

Protease

None Detected

None Detected

None Detected

None Detected

Identification, Chloride Passes Test
Identification, IR Conforms to Reference Standard
Insoluble Matter < = 0.001%
Loss on Drying < = 0.5%
Melting Range  149 - 153°C
Microbial Content

TAMC

TYMC

< 50 CFU/g

< 50 CFU/g

pH (1%) 4.2 - 4.9
Residue on Ignition < = 0.1%
Residual Solvents

Methanol

Nitromethane

< = 300 ppm

< = 50 ppm

Solubility (1M)  
Clear, Colorless Solution
Trace Metals

Aluminum (Al)

Arsenic (As)

Antimony (Sb)

Barium (Ba)

Bismuth (Bi)

Cadmium (Cd)

Calcium (Ca)

Chromium (Cr)

Cobalt (Co)

Copper (Cu)

Iron (Fe)

Lead (Pb)

Lithium (Li)

Maganese (Mn)

Magnesium (Mg)

Mercury (Hg)

Molybdenum (Mo)

Nickel (Ni)

Potassium (K)

Silver (Ag)

Sodium (Na)

Strontium (Sr)

Tin (Sn)

Zinc (Zn) 

< = 5 ppm

< = 10 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 1 ppm

< = 1 ppm

< = 5 ppm

< = 5 ppm

< = 1 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

< = 50 ppm

< = 5 ppm

< = 50 ppm

< = 5 ppm

< = 5 ppm

< = 5 ppm

Water Content (KF)  

< = 0.5%

 

Printable Version

Key Product Features:

  • Appears as a white crystalline product 
  • Manufactured in accordance with the ISO Certified Quality Management System 
  • Manufactured in an enzyme free, hormone free and animal free environment
  • Contains no known major food allergens (as defined by FDA and WHO)
  • The final product and its raw materials are not derived from nor come into contact with animal parts, animal products, and/or animal byproducts or derivatives. 
  • Is not subject to genetic modification
  • Synonyms: 2-Amino-2(Hydroxymethyl)-1,3-Propanediol Hydrochloride; Tri(Hydroxymethyl) Aminomethane Hydrochloride. 

Shelf-Life Policy:

Please inquire for information regarding shelf-life.

Storage & Shipping:

Refer to SDS.

Package Sizes:

1kg, 5kg, 10kg, 25kg, and 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.