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Excipient

ICH-Q7 GMP Manufactured Product

MOPS Free Acid

GMP, Excipient Grade

Minimum Order Quantity: 250kg Lead Time (if no stock): 3-6 months

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Product Code: MOPS-3220 | Previously: MP3220
Intended For Use As An Excipient

MOPS is a zwitterionic buffer used as a running buffer for denaturing gel electrophoresis and as a buffering agent in many biological and biochemical applications. MOPS interferes with the Folin protein assay and partially decomposes when autoclaved in the presence of glucose. MOPS can be used as a Good’s buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

CAS #: 1132-61-2
Formula: C7H15NO4S
Sol. In H2O (g/L): 980
F.W.: 209.26 g/mol
pH @ 20°C: 3.0 - 4.5
Useful pH: 6.5 - 7.9
pKa @ 20˚C: 7.2

Product Specifications

ANALYSIS SPECIFICATIONS
  250 nm
Absorbance (0.1M) 260 nm
  280 nm
0.020 a.u. maximum
0.020 a.u. maximum.
0.020 a.u. maximum
Appearance and Color  
White / Crystals
Assay  
99.5% min.
Chloride  
0.005% max.
Enzymes

DNase

RNase

Protease

None Detected
None Detected
None Detected
Identification (IR)  
Passes Test
Karl Fischer Water  
0.1% maximum
Loss on Drying  
1.0% maximum
pH (1% solution)  
3.0-4.5

pH (2.5M)

 
2.5-4.5
pKa  

7.0-7.5

Residue on Ignition  
0.1% maximum
Solubility (5%)  
Passes Test
Sulfate  
0.005% maximum
Trace Metals Arsenic (As)
Copper (Cu)
Iron (Fe)
Lead (Pb)
5 ppm maximum
5 ppm maximum
5 ppm maximum
5 ppm maximum

 

Printable Version

General Product Description:

  • The Manufacturing of MOPS MOPS-3220 is performed at BioSpectra’s Stroudsburg, PA facility and is conducted in a dedicated processing area using only dedicated equipment.
  • MOPS is a White Crystalline product.
  • Molecular Formula: C7H15NO4S
  • Molecular Weight: 209.26 g/mol.
  • CAS Number: 1132-61-2.
  • There are no known major food allergens (as defined by FDA and WHO) in the manufacture of this product.
  • BioSpectra certifies that all MOPS MOPS-3220 manufactured at BioSpectra and its raw materials are not derived from
    or come in contact with animal parts, products, and/or byproducts.
  • MOPS manufactured at BioSpectra and any raw materials used in the manufacture of MOPS at BioSpectra are not subject to genetic modification.
  • Synonyms: 3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid.

GMP Compliance:

Bio Excipient Grade MOPS MP3220 is manufactured in
accordance with cGMP guidelines and is suitable to be used only
as the following: ICH Q7 Compliant cGMP Manufactured Excipient
for use in further Manufacturing. This Grade of MOPS is not
suitable to be used as an Active Pharmaceutical Ingredient, Drug
Product or household item.

Retest Date:

The recommended retest period for MOPS is two years from the
date of manufacture.

Storage and Shipping Conditions:

Ship and Store in ambient temperature.

Package Sizes:

10kg, 25kg and 50kg pails.

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.