HEPES, FREE ACID BIOTECH

GMP Biotech Product

HEPES, FREE ACID BIOTECH

LBLE*, GMP
Product Code: HEPE-4250

*Low Bioburden, Low Endotoxin

Product Inquiry COAs Spec Sheet

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Price per unit (USD)				Price per kilogram (USD)
100g	500g	1kg	2-5kg (1kg ea)	1x5kg	1x10kg
$95 ea.	$275 ea.	$255 ea.	$235 ea.	$215 /kg	$195 /kg

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UNIT SIZE

QUANTITY

100g

500g

1kg

2-5kg

1x5kg

1x10kg

Total

Product Code: HEPE-4250

Intended for Use in Biopharmaceutical & Biotechnological Applications and Products

HEPES, Free Acid is used as a high purity, GMP Reagent grade product. HEPES, Free Acid is a zwitterionic buffer used to maintain pH of media used in cell cultures. It is one of Good’s twelve buffers that has a pKa value similar to its pH value making it an ideal buffer for pH maintenance. HEPES is used as a Good’s buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

Formula: C₈H₁₈N₂O₄S
F.W.: 238.30 g/mol
CAS #: 7365-45-9

Product Specifications

ANALYSIS

SPECIFICATIONS

Absorbance (0.1M)

250 nm

260 nm

280 nm

< = 0.0500 a.u.

< = 0.0800 a.u.

Absorbance (0.5M)

250 nm

260 nm

280 nm

< = 0.0500 a.u.

< = 0.0800 a.u.

Appearance and Color

White Crystals

Assay, Dried Basis

> = 99.5%

Chloride

< = 50 ppm

Endotoxin

< = 5 EU/g

Enzymes

DNase

RNase

Protease

None Detected

Identification, IR

Conforms to Reference Standard

Insoluble Matter

< = 0.01%

Loss on Drying

< = 0.5%

Microbial Content

TAMC

TYMC

< = 100 CFU/g

pH (5%)

5.0 - 6.5

pKa

7.45 - 7.65

Residue on Ignition

< = 0.1%

Solubility

Solubility (5%)

Solubility (0.05M)

Passes Test

Sulfate

< = 50 ppm

Trace Metals

Arsenic (As)

Aluminum (Al)

Bismuth (Bi)

Calcium (Ca)

Copper (Cu)

Iron (Fe)

Lead (Pb)

Lithium (Li)

Molybdenum (Mo)

Nickel (Ni)

Potassium (K)

< = 5 ppm

< = 10 ppm

< = 5 ppm

< = 1 ppm

< = 5 ppm

< = 50 ppm

Water, KF

< = 0.1%

Printable Version

General Product Description:

Molecular Formula: C₈H₁₈N₂O₄S
Molecular Weight: 238.30 g/mol
CAS Number: 7365-45-9
Appears as a white crystalline product
Manufactured in accordance with IPEC
Manufactured in an enzyme free, hormone free and animal free environment
Contains no known major food allergens (as defined by FDA and WHO)
The final product nor its raw materials are not derived from nor come into contact with animals, animal parts, animal products, and/or animal byproducts or derivatives.
Is not subject to genetic modification
Synonyms: N-(2-Hydroxyethyl) piperazine-N’-2-ethane sulfonic acid, 2-[4-(2-hydroxyethyl)piperazin-1-yl] ethane sulfonic acid.

Shelf Life Policy:

Each Certificate of Analysis (CoA) will contain a 2-year retest date supported by a 3-year ICH Q1 Stability Study (if one is completed).

Storage and Shipping Conditions:

Please refer to the SDS for storage and shipping conditions.

Package Sizes:

100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.