Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures. These are general specifications. BioBuffer Solutions will customize our products to meet your quality based requirements.
| ANALYSIS | SPECIFICATIONS |
|---|---|
|
280 nm Absorbance 300 nm 340 nm |
0.400 a.u. max. 0.070 a.u. max. 0.050 a.u. max. |
| Appearance and Color | White / Crystals |
| Assay, Dried Basis | 99.0% min. |
| Identity (FTIR) | Passes Test |
| Melting Range | 115 – 121 ºC |
| pH (5% solution) | 5.0 – 7.0 |
| Solubility (35% solution) | Passes Test |
Printable Version
Material represented by this grade is suitable to be used only as the following: Quality System Manufactured Process Chemical for use in further manufacturing or as a reagent for laboratory and research. The material represented by this grade is not suitable to be used as an Excipient, Active Pharmaceutical Ingredient, Drug, Drug Product or household item.
BioBuffer Solutions does not assign expiration or retest dates for Bio Ultra Grade materials.
Ship and Store in ambient temperature.
10kg, 25kg and 50kg pails.
American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.