Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. As a chaotropic agent, it breaks down the structure of proteins. Guanidine Hydrochloride is commonly used in the purification of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations, Guanidine Hydrochloride decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules. These are general specifications. BioBuffer Solutions will customize our products to meet your quality based requirements.
| ANALYSIS | SPECIFICATIONS |
|---|---|
|
260 nm Absorbance 275 nm 230 nm |
0.0500 a.u. maximum 0.0500 a.u. maximum 0.3000 a.u. maximum |
| Appearance and Color | White / Crystals |
| Assay | 99.0% min. |
| Identification (IR) | Passes Test |
| Melting Range | 184-188ºC |
| pH (6M) | 4.5-6.0 |
| Residue on Ignition | 0.05% maximum |
| Solubility | Passes Test |
Printable Version
Material represented by this grade is suitable to
be used only as the following: Quality System
Manufactured Process Chemical for use in further
manufacturing or as a reagent for laboratory and
research. The material represented by this grade
is not suitable to be used as an Excipient, Active
Pharmaceutical Ingredient, Drug, Drug Product or
household item.
BioBuffer Solutions does not assign expiration or retest dates for Bio Ultra Grade materials.
Ship and Store in ambient temperature.
10kg, 25 kg and 50 kg pails.
American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.