Guanidine HCL
Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. As a chaotropic agent, it breaks down the structure of proteins. Guanidine Hydrochloride is commonly used in the purification of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations, Guanidine Hydrochloride decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules. These are general specifications. BioBuffer Solutions will customize our products to meet your quality based requirements.
Product Specifications
| ANALYSIS | SPECIFICATIONS |
|---|---|
|
260 nm Absorbance 275 nm 230 nm |
0.0500 a.u. maximum 0.0500 a.u. maximum 0.3000 a.u. maximum |
| Appearance and Color | White / Crystals |
| Assay | 99.0% min. |
| Identification (IR) | Passes Test |
| Melting Range | 184-188ºC |
| pH (6M) | 4.5-6.0 |
| Residue on Ignition | 0.05% maximum |
| Solubility | Passes Test |
Printable Version
General Product Description:
- Guanidine HCl is a White Crystalline product.
- Molecular Formula: CH5N3 . HCL
- Molecular Weight: 95.53 g/mol.
- CAS Number: 50-01-1.
- Synonyms: Guanidine Monohydrochloride, Guanidinium Chloride, Guanidinium Hydrochloride.
Intended Use Statement:
Material represented by this grade is suitable to
be used only as the following: Quality System
Manufactured Process Chemical for use in further
manufacturing or as a reagent for laboratory and
research. The material represented by this grade
is not suitable to be used as an Excipient, Active
Pharmaceutical Ingredient, Drug, Drug Product or
household item.
Expiration/Retest Date:
BioBuffer Solutions does not assign expiration or retest dates for Bio Ultra Grade materials.
Storage and Shipping Conditions:
Ship and Store in ambient temperature.
Package Sizes:
10kg, 25 kg and 50 kg pails.
Bulk GMP Fine Chemicals exclusively manufactured in North America
American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.