GMP Manufactured Process Chemical
Guanidine Hydrochloride 6M solution can be used to denature proteins which become randomly coiled with no residual structure. This concentration is also used to decrease enzyme activity. The denatured proteins can be modified or analyzed using mass spectrometry, electrophoresis and enzymatic digests. As a chaotropic agent, Guanidine Hydrochloride solution is also used to break the hydrogen bonds in the structure of proteins and increase the solubility of hydrophobic molecules.
CAS #: 50-01-1
Formula: CH5N3 • HCl
Sol. In H20 (g/L): 573
F.W.: 95.53 g/mol
pH @ 20oC: 4.5 - 6.0
pKa @ 25oC: 13.6
| ANALYSIS | SPECIFICATIONS | ||
|---|---|---|---|
|
Clear, Colorless Liquid | ||
|
< 10 ppm | ||
|
Passes Test | ||
|
≤ 3 ppm | ||
|
5.5-6.5 M |
Printable Version
Bio Pharma Grade Guanidine Hydrochloride 6M, GHCL-4120 is suitable for use as a process chemical. It is manufactured in accordance with the IPEC- PQG Joint Good Manufacturing Practice Guide. This grade of Guanidine Hydrochloride is not suitable to be used as an Active Pharmaceutical Ingredient, Drug, Drug Product or Household Item.
The recommended retest period for Guanidine Hydrochloride 6M is two years from the date of manufacture.
Ship and Store in ambient temperature.
Available in 200L drums and totes.
American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.