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GMP Biotech Product

TRIS BIOTECH

High Assay, USP, GMP
Product Code: TRIS-4223

Product Inquiry COAs Spec Sheet

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Price per unit (EUR)				Price per kilogram (EUR)
100g	500g	1kg	2-5kg (1kg ea)	1x5kg	1x10kg
€169 ea.	€288.60 ea.	€279.40 ea.	€261 ea.	€242.60 /kg	€233.40 /kg

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UNIT SIZE

QUANTITY

100g

500g

1kg

2-5kg

1x5kg

1x10kg

Total

Product Code: TRIS-4223

Suitable for use in biological and biotech chemical process applications from R&D through scale cGMP production.

This product is used when high purity, high assay, GMP grade Tris/Tromethamine is required. Tris is considered a Good’s buffer because it has low UV absorptivity, minimum reactivity, stable pH and is soluble in water.

Formula: NH₂C(CH₂OH)₃F.W.: 121.14 g/mol
CAS #: 77-86-1

Product Specifications

ANALYSIS

SPECIFICATIONS

Absorbance (1M)

260nm

280nm

430nm

< = 0.06 a.u.

< = 0.01 a.u.

Absorbance (10%)

260nm

280nm

430nm

< = 0.03 a.u.

< = 0.02 a.u.

< = 0.004 a.u.

Absorbance (40%)

290nm

< = 0.20 a.u.

APHA Color (20% Solution)

< = 20 APHA

Assay, Dried Basis (USP)

99.0 - 101.0%

Assay, Dried Basis (Ultrapure)

> = 99.9%

Chloride

< = 20 ppm

Endotoxin

< = 2.5 EU/g

Enzymes

DNase

Protease

RNase

None Detected

Identification A, IR (USP)

Conforms to Reference Standard

Identification B (USP)

Passes Test

Identification C (USP)

Passes Test

Insoluble Matter

< = 0.005%

Loss on Drying (USP)

< = 0.3%

Melting Range (USP)

168 – 172°C

Microbial Content

TAMC

TYMC

< = 100 CFU/g

pH (5%) (USP)

10.0 – 11.5

Related Substances

< = 0.1%

Residue on Ignition (USP)

< = 0.05%

Trace Metals

Aluminum (Al)

Arsenic (As)

Barium (Ba)

Bismuth (Bi)

Cadmium (Cd)

Calcium (Ca)

Chromium (Cr)

Cobalt (Co)

Copper (Cu)

Iron (Fe)

Lead (Pb)

Lithium (Li)

Magnesium (Mg)

Manganese (Mn)

Molybdenum (Mo)

Nickel (Ni)

Potassium (K)

Sodium (Na)

Zinc (Zn)

< = 5 ppm

< = 1.6 ppm

< = 5 ppm

< = 1 ppm

< = 5 ppm

< = 1 ppm

< = 5 ppm

< = 1 ppm

< = 5 ppm

< = 50 ppm

< = 1 ppm

Water, KF

< = 1.0%

Printable Version

Key Product Features:

Appears as a white crystalline product
Manufactured in accordance with IPEC
Manufactured in an enzyme free, hormone free and animal free environment
Contains no known major food allergens (as defined by FDA and WHO)
The final product and its raw materials are not derived from nor come into contact with animals, animal parts, animal products, and/or animal byproducts or derivatives.
Is not subject to genetic modification
Synonyms: Tris(hydroxymethyl) aminomethane; Trometamol; THAM; Trisaminol; Tromethamine

Shelf-Life Policy:

Unless otherwise noted on the Shelf-Life Statement and CoA, this product has a 2-year retest date supported by a 3-year ICH Q1 Stability Study (if one is completed).

Storage & Shipping:

Refer to SDS.

Package Sizes:

100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.