Camida is a specialist supplier of raw materials the Life Sciences, Ingredients, and Industrial sectors. Known for our customer-focused approach and technical expertise, we deliver tailored solutions to our customers worldwide.

We are proud of our long-standing partnership with BioSpectra, working together to deliver high-quality, GMP and pharmaceutical-grade ingredients to the BioTech sector. Our shared commitment to excellence and reliability ensures customers have access to an extensive, trusted product range tailored to their specific needs.

If you would like to learn more or discuss how we can support your requirements, please get in touch with us today.

Click Here to Return to CAMIDA Website

GMP Biotech Product

BIS-TRIS BIOTECH

LBLE*, GMP
Product Code: BTRI-4250

*Low Bioburden, Low Endotoxin

Product Inquiry COAs Spec Sheet

Click the button above for additional pricing, lead times, MOQs and other inquiries.

Product Inquiry

Product(s) of Interest *

First Name *

Last Name *

Title & Position in Company *

Email *

Your Direct Phone Number & Country Code *

Name of Your Company *

Website of Your Company *

Address of Company *

Country where product is to be used *

Name of Your Customer – the End User *

Website of Your Customer – the End User *

Intended Application/Use if known

Package Size Requested *

Estimated Release Quantity per PO in Liters or Kgs *

Estimated Annual Demand in Liters or Kgs *

Regulatory or Compendial Requirements *

INCO Terms requested *

Price per unit (EUR)				Price per kilogram (EUR)
100g	500g	1kg	2-5kg (1kg ea)	1x5kg	1x10kg
€219.60 ea.	€422 ea.	€408.20 ea.	€389.80 ea.	€371.40 /kg	€362.20 /kg

End Users, please use the button below to initiate an order request. The form will download to Customer Service who will follow up with payment options or other information as needed. Please note: no payment will be required at this point.

Customer Service CAMIDA

First Name *

Last Name *

Company Name *

Position in Company

Email *

Company website

Company phone with country code *

Country where product is to be used *

Street Address *

City *

State *

Zip Code *

Country *

Additional Information Needed/Requested

UNIT SIZE

QUANTITY

100g

500g

1kg

2-5kg

1x5kg

1x10kg

Total

Product Code: BTRI-4250

Intended for Use in Biopharmaceutical & Biotechnological Applications and Products

Intended to be used as a high purity, GMP Reagent Grade. BIS-TRIS is a zwitterionic biological “Goods” buffer often used in biological pharmaceutical manufacturing and biochemistry for extraction, separation and purification, as well as an intermediate in synthetic reactions for both proteins and nucleic acid. BIS-TRIS is also used as a process aid in peptide synthesis. It can also be used as a scavenger agent for metal ions such as Cu and Pb.

CAS #: 6976-37-0
Formula: C₈H₁₉NO₅pH @ 25°C: 6.3 - 6.7
Melting Point/Range: 100 - 105°C
F.W.: 209.24 g/mol

Product Specifications:

Analysis

Specifications

Enzymes

DNase

Protease

RNase

None Detected

Trace Metals

Aluminum (Al)

Calcium (Ca)

Iron (Fe)

Lead (Pb)

Phosphorus (P)

≤ 5 ppm

≤ 500 ppm

≤ 3 ppm

≤ 10 ppm

≤ 500 ppm

Appearance and Color

White Crystalline Powder

Assay, Dried Basis

99.0% - 101.0%

Bioburden

TAMC

TYMC

≤ 100 CFU/g

Chloride

≤ 50 ppm

Endotoxin

≤ 50 EU/g

Absorbance (0.1M)

280nm

340nm

≤ 0.04 a.u.

≤ 0.02 a.u.

Heavy Metals (Pb)

≤ 3ppm

Identification (IR)

Conforms to Reference Standard

Loss on Drying

≤ 1.0%

Melting Point

100 – 105°C

pH (1% aqueous)

8.8 – 9.8

pKa

6.3 – 6.7

Residue on Ignition

≤ 0.1%

Solubility 0.1M in H₂O

Clear & Complete

Water (KF)

≤ 1.0%

Ammonium (NH₄)

≤ 500 ppm

Sulfate

≤ 50 ppm

Printable Version

General Product Description:

Molecular Formula: C₈H₁₉NO₅Molecular Weight: 209.24 g/mol
CAS Number: 6976-37-0

BIS-TRIS Biotech:

Appears as a white crystalline product.
Is manufactured under an ICH-Q7 Quality Managed cGMP System
Manufactured in an enzyme free, hormone free and animal free environment
Has no known major food allergens (as defined by FDA and WHO)
The final product nor its raw materials are not derived from nor come into contact with animals, animal parts, animal products, and/or animal byproducts or derivatives.
Is not subject to genetic modification
Synonyms: 2,2-Bis(hydroxymethyl)-2,2’,2’’- nitrile tri ethanol; Bis(2-hydroxyethyl) amino tris (hydroxymethyl)methane

Shelf Life Policy:

Each Certificate of Analysis (CofA) will contain a 2-year retest/recertification date supported by a 3-year ICH Q1 Stability Study (if one is completed).

Storage and Shipping Conditions:

Please refer to the SDS for storage and shipping conditions.

Package Sizes:

100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg.

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.