Biological Buffers ~ All Biological Buffers ~ GUANIDINE THIOCYANATE
|CAS #: 593-84-0|
|Molecular Formula: C2H6N4S|
|Solubility in Water (g/L): 1,600|
|F.W.: 118.16 g/mol|
|pH @ 20°C: 5.0 - 7.0|
|Hazardous Product: yes|
Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.
Key Compliance Attributes:
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